Flow Chemistry
This research area involves the design and test of fixed-bed and monolithic microreactors using organo- and bio-catalysts immobilized on silica or polystyrene as packing materials. The development of continuous-flow processes by the microreactor technology allows for the synthesis of high added-value molecules on the milligram-multigram scale with improved efficiency, sustainability, and lower costs compared to traditional batch processes.
Goals
- Study of the immobilization strategy of the (bio)organocatalyst.
- Physicochemical characterization of the (bio)material.
- Fabrication of fixed-bed microreactors and monolithic columns.
- Development of new stereoselective carboligation reactions in flow regime.
- Reaction modeling for process optimization.
Instruments and Methods
Mass (MS) spectrometry and infrared (FT-IR) spectroscopy. Nuclear magnetic resonance (NMR). Elemental analysis. Chromatographic instruments. Scanning electron microscopy (SEM).
Main Subjects
Organic chemistry; biochemistry; analytical chemistry; process chemistry.
Research Group
- Olga Bortolini
- Alessandro Massi
- Pier Paolo Giovannini
- Daniele Ragno
- Carmela De Risi
Collaborations
- Prof. D. Belder (University of Lipsia, Germany)
- Dr. P. Dambruoso (CNR-ISOF, Bologna)
- Prof. O. Pandoli (Pontifícia Universidade Católica do Rio de Janeiro, Brasil)
